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Treacher Collins syndrome (TCS), also known as Treacher Collins–Franceschetti syndrome, or mandibulofacial dysostosis is a rare autosomal dominant congenital disorder characterized by craniofacial deformities, such as absent cheekbones.:577 Treacher Collins syndrome is found in about 1 in 50,000 births. In a number of cases a genetic origin is described. The typical physical features include downward slanting eyes, micrognathia (a small lower jaw), conductive hearing loss,

treacher collens syndrome